·糖尿病与心血管病·

　　【摘要】 目的 急性冠状动脉综合征(ACS)及合并T2DM患者非罪犯病变的血管内超声-虚拟组织学(IVUS-VH)特点与罪犯病变进行比较，为临床处理非罪犯病变提供参考。方法 选取ACS患者60例，其中17例合并T2DM，入选者分别行3条血管IVUS-VH检查，测量病变的IVUS-VH指标，检出薄纤维帽粥样斑块(VH-TCFA)，确定罪犯病变后分为罪犯病变组与非罪犯病变组进行比较。结果 两组VH-TCFA检出率一致(66.7% vs 66.7%，P=1.000)。结论 ACS患者(部分合并T2DM)非罪犯病变同样具有易损性。

　　【关键词】 急性冠状动脉综合征;糖尿病，2型;血管内超声-虚拟组织学;非罪犯病变

Intravascular ultrasound and virtual histology study on nonculprit lesion in acute coronary syndrome patients and some of them with type 2 diabetes mellitus ZHENG Jie-shu，ZHANG Yuan-chun，HE Xun，et al. Department of Cardiology，The Affiliated Tungwah Hospital, Sun Yat-Sen University, Dongguan 523110, China

Corresponding author: ZHANG Yuan-chun, E-mail: yuanchunzhang@21cn.com

　　【Abstract】Objective To compare the characteristics of non-culprit lesion with those of culprit lesion in acute coronary syndrome (ACS) patients and when some of them were accompanied with T2DM to provide the references for the clinical management of non-culprit lesion. Methods The 3-vessel intravascular ultrasound and virtual history (IVUS-VH) analysis was performed for 60 ACS patients, 17 of them with T2DM. The parameters of IVUS-VH were measured for all the lesions. The thin-cap fibroatheromas (VH-TCFA) were detected. After the culprit lesion was diagnosed first, the culprit and nonculprit lesion groups were compared to observe the characteristics between them. Results The detectable rate of IVUS-VH derived thin-cap fibroatheroma (VH-TCFA) in the nonculprit and culprit lesion groups was the same (66.7% vs 66.7%, P=1.000). Conclusion Nonculprit lesion was vulnerable in ACS patients (some of them with T2DM).

　　【Key words】Acute coronary syndrome (ACS); Diabetes mellitus, type 2; Intravascular ultrasound and virtual history (IVUS-VH); Nonculprit lesion