·糖尿病与心血管病·

　　【摘要】 目的 回顾性研究2006～2008年我院行经皮冠状动脉介入治疗(PCI)的急性心肌梗死(AMI)患者在院平均血糖水平与在院死亡的关系。 方法 单因素和多因素logistic回归模型对平均血糖值、年龄等11个候选因素进行分析。 结果 单因素logistic回归分析发现在院平均血糖升高(Waldχ2=11.883，p=0.001)、增龄(Waldχ2=17.336，p=0.000)、低HDL-C血症(Waldχ2=4.024，p=0.045)可能是AMI患者在院死亡的危险因素。多因素logistic回归分析提示在院平均血糖值(Waldχ2=10.266, OR=1.69)、增龄(Waldχ2=13.604, OR=5.24)是AMI患者在院死亡的主要危险因素。 结论 在院平均血糖水平高、增龄是已行PCI治疗的AMI患者在院死亡的主要独立危险因素。

　　【关键词】 急性心肌梗死;平均血糖;增龄;在院死亡

Analysis on the independent risk factors of the mortality in patients hospitalized with acute myocardial infarction LI Yan-li, SHEN Yun-feng, ZHENG Jia, et al. Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.

Corresponding author: SHEN Yun-feng, E-mail: syf@medmail.com.cn

　　【Abstract】 Objective To study retrospectively the relation between the average blood glucose levels and hospitalized mortality of the patients hospitalized with acute myocardial infarction (AMI) treated by percutaneous coronary intervention (PCI) in the duration from 2006 to 2008 in our hospital. Methods By using the univariate and multivariate logistic regression analyses, the 11 factors, including average blood glucose level, age, etc., were applied to screen the possible risk factors of the mortality in patients hospitalized with AMI. Results In the univariate logistic regression analysis, it was discovered that the higher average blood glucose level (Wald χ2=11.883, P=0.001), aging (Wald χ2=17.336, P=0.000), and low HDL-C (Wald χ2=4.024, P=0.045) were the potential predictors of mortality for patients hospitalized with AMI. The multivariate logistic regression analysis showed that both the higher average blood glucose level (Wald χ2=10.266, OR=1.69) and aging (Wald χ2=13.604, OR=5.24) were the prominent risk factors for hospitalized death. Conclusion Both the higher average blood glucose level in hospital and aging are the prominent risk factors of the mortality in hospitalized patients with AMI treated by PCI.

　　【Keywords】 Acute myocardial infarction;Average blood glucose level; Aging; Hospitalized mortality