·糖尿病临床流行病学·

　　【摘要】 目的 探讨湖北省宜昌市夷陵区农村T2DM患者糖尿病周围神经病变(DPN)患病状况及相关因素。 方法 多级分层抽样调查夷陵区农村T2DM患者，予问卷调查、体格检查、实验室检查和特殊检查后录入数据，根据有无DPN分为DPN组及非DPN(Non-DPN)组进行分析。 结果 夷陵区农村T2DM患者DPN患病率约为59.8%，两组年龄、糖尿病病程、腰高比和踝臂指数(ABI)比较差异均有统计学意义(P<0.05)。Logistic回归分析显示，DPN患病率与年龄、性别、糖尿病病程、腰高比、ABI、FPG和FIns有关。 结论 宜昌市夷陵区农村T2DM患者DPN患病率较高，年龄、糖尿病病程、腰高比、ABI和FPG是该地区T2DM患者DPN的相关因素。

　　【关键词】糖尿病，2型; 糖尿病周围神经病变; 宜昌市夷陵区农村; 患病率; 相关因素

Prevalence and relevant factors of diabetic peripheral neuropathy in type 2 diabetes patients in rural areas of Yiling District  Yichang LI Shou-hua, HU Xiang, SHENG Xia, et al. Department of Endocrinology, Yiling Hospital, Yichang 443100, China

Corresponding author: CHEN Lu-lu, E-mail: cheria_chen@126.com

　　【Abstract】 Objective To explore the prevalence and relevant factors of diabetic peripheral neuropathy in T2DM patients lived in rural areas of Yiling District, Yichang. Methods A multistage stratified sampling were employed in the T2DM patients lived in the rural areas of Yiling District, Yichang, Hubei Province. The questionnaire survey, physical examination, laboratory tests, and special examinations were performed, and all data were collected. The patients were divided into two groups for statistical analysis: diabetic peripheral neuropathy (DPN) group and non-diabetic peripheral nerve lesions (Non-DPN) group. Results The prevalence of diabetic peripheral neuropathy in T2DM patients in the rural areas of Yiling District was approximately 59.8%. Significant differences were observed in age, T2DM duration, waist height ratio and ankle-brachial index (ABI) between the two groups (P<0.05). Logistic regression analysis determined that age, gender, diabetes duration, waist to height ratio, ABI, FPG, and FIns were significantly correlated with DPN. Conclusion The prevalence of diabetic peripheral neuropathy in T2DM patients was high in the rural area of Yiling District, Yichang. In this population-based study, the age, gender, diabetes duration, waist to height ratio, and ABI and FPG levels are important relevant factors of diabetic peripheral neuropathy in T2DM patients in this region.

　　【Key words】 Diabetes mellitus, type 2; Diabetic peripheral neuropathy (DPN); Rural areas of Yiling District, Yichang; Prevalence; Relevant factors