【摘要】目的：探寻老年T2DM下肢深静脉瓣功能不全与下肢周围神经病变的关系。方法：对43例老年T2DM患者,行下肢静脉二维彩色多普勒超声检查及肌电图检查，按静脉瓣功能不全程度分组进行秩相关分析。结果：右腓运动神经潜伏期与下肢静脉瓣功能不全程度呈正相关(P<0.05), 左腓、双胫运动神经潜伏期与下肢静脉瓣功能不全程度呈显著正相关(P<0.01);左腓感觉神经传导速度与下肢静脉瓣功能不全程度呈负相关(P<0.05)，双腓运动神经传导速度、双胫及右腓感觉神经传导速度与下肢静脉瓣功能不全程度呈显著负相关(P<0.01)。结论：下肢深静脉瓣功能不全程度可能与下肢周围神经病变程度相关。

　　【关键词】糖尿病,2型;下肢;静脉功能不全;糖尿病神经病变; 糖尿病足

　　Clinical analysis on the association between lower limb venous valve insufficiency and lower limb peripheral neuropathy in elderly T2DM patients ZHANG Lin, SHEN Yun, BI Hong-yan, et al. The Geriatrics Department, the First Affiliated Hospital of Kunming Medical College, Kunming 650032, China

　　Corresponding author: ZHANG Lin, E-mail: zhanglin2233@126.com

　　【Abstract】Objective To study the association between lower limb venous valve insufficiency and lower limb peripheral neuropathy in elderly T2DM patients. Methods The function of lower extremity deep venous valves of 43 elderly T2DM patients were checked with color Doppler ultrasound and electromyography. An analysis on the rank correlation of venous valve function with peripheral neuropathy was performed according to the different degrees of venous valve insufficiency. Results Latency of the right peroneal motor nerve was positively correlated with the degree of lower limb venous valve insufficiency (P<0.05). Latency of the left peroneal motor nerve and bilateral tibial motor nerves was positively correlated in significance with the degree of lower limb venous valve insufficiency (P<0.01). Sensory nerve conduction velocity of the left peroneal nerve was negatively correlated with the degree of lower limb venous valve insufficiency (P<0.05). Motor nerve conduction velocity of bilateral peroneal nerves and sensory nerve conduction velocity of bilateral tibial nerves and the right peroneal nerve were negatively correlated in significance with the degree of lower limb venous valve insufficiency (P<0.01). Conclusion The degree of lower limb venous valve insufficiency is probably correlated with the degree of lower limb peripheral neuropathy.

　　【Key words】 Diabetes mellitus, type 2; Lower extremity; Venous insufficiency; Diabetic neuropathy; Diabetic foot