·糖尿病与营养·

　　刘健 冯翔 何影仪 肖新才 陈思凡 杨雪霞 谭燮文 郑敏玲

　　基金项目：广州市番禺区科技局2008年度科技攻关项目(2008-Z-90-1)

　　作者单位：511490广州，广州市番禺疗养院);中山大学公共卫生学院，广东省营养膳食与健康重点实验室

　　通讯作者：冯翔，E-mail：fengx@mail.sysu.edu.cn

　　【摘要】目的调查和分析广州地区T2DM的膳食危险因素，为本地区T2DM的防治提供科学依据。方法采取病例对照方法在体检人群中选取新诊断的T2DM病例和对照，每组126例，进行膳食问卷调查，同时进行血清生化及一般体格检查，分析两组间各变量差异，分析T2DM膳食危险因素。结果病例组每日摄入能量(2867.75±748.04)kcal、脂肪(95.99±19.85)g、蛋白质(100.59±29.85)g、膳食胆固醇(334.92 ± 94.63)mg，均显著高于对照组;血清TG、SBP和DBP均高于对照组(P<0.05);膳食纤维每日摄入量则显著低于对照组(P=0.011);两组糖类每日摄入量、血清TC、HDL-C和LDL-C的差异均无统计学意义。结论广州地区人群T2DM的独立危险因素包括膳食脂肪、维生素A、TG及遗传，独立保护因素包括膳食纤维、维生素E、维生素B1、钙摄入和运动。

　　【关键词】糖尿病，2型;膳食;病例对照;危险因素

　　doi:10.3969/j.issn.1006-6187.2012.01.005

　　Study of the dietary risk factors in newly diagnosed T2DM patients in Guangzhou districtLIU Jian, FENG Xiang, HE Ying-yi, et al. Guangzhou Panyu Snantorium, Guangzhou 511490, China

　　Corresponding author: FENG Xiang, E-mail: fengx@mail.sysu.edu.cn

　　【Abstract】ObjectiveTo investigate the dietary risk factors in T2DM population in Guangzhou district. MethodWe selected newly-diagnosed T2DM cases (n=126) and healthy controls (n=126), applied the food frequency questionnaire investigation, and measured TC, TG, HDL, LDL and carried out physical examination, and analyzed the differences between the two groups. ResultsThe daily intakes included: energy (2867.75±748.04)kcal, fat (95.99±19.85)g, protein (100.59±29.85)g, and dietary cholesterol (334.92±94.63)mg. Serum TG, systolic pressure and diastolic pressure were significantly higher in case group than in control group (P<0.05), while the intake of dietary fiber was significantly lower in case group (P=0.011). The differences between the two groups in the aspects of the intakes of carbohydrate, serum TC, HDL-C and LDL-C were not significant (P=0.07). ConclusionThe risk of T2DM decreases by controlling energy intake, depressing the ratio of fatty energy. The dietary pattern may contribute to the increasing prevalence of T2DM in this area.

　　【Key words】Diabetes mellitus, type 2; Diet; Case control; Risk factors