·糖尿病大血管病变·

　　【摘要】 目的 利用实时三维超声心动图(RT-3DE)评价T2DM患者左室收缩功能及同步性。 方法 选取T2DM患者60例，根据BP水平分为T2DM合并高血压(HT)(T2DM+HT)组28例及单纯T2DM组(T2DM)32例，另设正常对照(NC)组30名，均行常规二维超声心动图及RT-3DE检查。 结果 T2DM+HT组及单纯T2DM组RT-3DE测量的左室射血分数(LVEF)均低于NC组(P均<0.05);与NC组相比，T2DM+HT组及单纯T2DM组左室容积-时间曲线各参数(Tmsv16-SD、Tmsv12-SD、Tmsv6-SD、Tmsv16-Dif、Tmsv12-Dif、Tmsv6-Dif、Tmsv16-SD%、Tmsv12-SD%、Tmsv6-SD%、Tmsv16-Dif%、Tmsv12-Dif%、Tmsv6-Dif%)均较NC组增大(P均<0.05)。 结论 应用RT-3DE技术可早期、准确评价T2DM患者左室收缩功能及其收缩不同步性。

　　【关键词】 糖尿病;超声心动描记术,实时三维;左室心功能;同步性

　　【Abstract】 Objective To evaluate left ventricular function and its synchronism with real-time three-dimensional echocardiography (RT-3DE) in type 2 diabetes mellitus. Methods 60 patients with type 2 diabetes mellitus were divided into T2DM with hypertension (DM+HT) group and T2DM without hypertension (T2DM) group, and 30 health adults were selected as normal control (NC) . Two-dimensional echocardiography and RT-3DE image data were acquired in all patients. Results LVEF measured with RT-3DE was lower in the T2DM+HT and T2DM group than in NC group(P<0.05); Left ventricular capacity-time curve parameters (including Tmsv16-SD，Tmsv12-SD，Tmsv6-SD，Tmsv16-Dif，Tmsv12-Dif，Tmsv6-Dif，Tmsv16-SD%，Tmsv12-SD%，Tmsv6-SD%，Tmsv16-Dif%，Tmsv12-Dif%，Tmsv6-Dif%) were significantly higher in T2DM and in T2DM+HT group than in NC group(P<0.05). Conclusions Real-time three-dimensional echocardiography can early evaluate left ventricular function and its synchronism in type 2 diabetes mellitus.

　　【Key words】 Diabetes mellitus; Echocardiography, real-time three-dimensional; Left ventricular function; Left ventricular synchronism

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