【摘要】 脂肪胰以胰腺脂肪浸润或胰腺脂肪变性为主要表现，其病理生理学机制目前尚未完全明确，国内外也尚未形成统一的诊断标准或共识。组织学检查是脂肪胰诊断的金标准，临床上MRI、CT和腹部超声都能发现替代胰腺实质的脂肪组织，EUS对脂肪胰的诊断具有独特的优势。已有多项研究表明脂肪胰与肥胖、T2DM、代谢综合征等代谢相关性疾病有关，胰腺脂肪变性的胰腺癌患者更易发生淋巴结转移及胰腺手术后的胰瘘，提示脂肪胰在以上疾病的诊断、治疗和预后判断上都有潜在的价值，可能成为如糖尿病、代谢综合征等代谢性疾病早期干预的指征之一。

　　【关键词】 脂肪胰;肥胖;代谢综合征;糖尿病

　　【Summary】 The main performance of fatty pancreas is fatty infiltration of pancreas or pancreas steatosis. The pathologic physiology mechanism of fatty pancreas is not yet completely clear, and the unified diagnostic standard or consensus has also yet to be formed. Histological examination is the gold standard for diagnosis. MRI, CT and ultrasound can find adipose tissue in the pancreas parenchyma, and endoscopic US (EUS) has unique advantages in the diagnosis of fatty pancreas. A number of studies have shown that many metabolic diseases, such as obesity, type 2 diabetes and metabolic syndrome, are all related to fatty pancreas. Change of lymph node metastasis and pancreatic fistula after surgery occurred more often in patients with fatty pancreas. So fatty pancreas have potential value in the diagnosis, treatment and prognosis judgment of the above disease, and might become one of the early intervention of indications of metabolic diseases.

　　【Key words】 Fatty Pancreas; Obesity; Metabolic syndrome; diabetes