·病例分析·

　　【摘要】 目的 提高临床医师对暴发性1型糖尿病(FDM)的认识。 方法 回顾性分析2003年10月至2012年10月我院收治的FDM患者的临床资料。 结果 年龄21～46岁,起病时随机血糖大于24 mmol/L，HbA1c 5.1%～7.6%。1～5 d迅速发展至糖尿病酮症酸中毒(DKA)。 结论 FDM发病急骤，代谢异常严重，胰岛β细胞功能受损严重，易合并并肾、心脏、肌肉等多脏器的功能损害，需引起临床医师的高度重视。

　　【关键词】 血红蛋白A;糖尿病,1型,暴发性

　　【Abstract】 Objective To enhance the understanding of fulminant type 1 diabetes mellitus(FDM). Methods Clinical and laboratory data of patients diagnosed as FDM in our hospital from October 2003 to October 2012 were retrospectively analyzed. Results (1)Aged 21～46 years old.(2)All patients were developed to diabetic ketoacidosis (DKA) rapidly in 1～5 days.(3)At the stage of onset，the plasma glucose level were above 24 mmol/L，glycosylated hemoglobin ranged 5.1%～7.6%. Conclusion FDM patients have clinical feathers of abrupt onset， metabolic disorder， islet β-cell function impaire，combine with multiple organ impair，which requires all medical practitioners pay more attention.

　　【Key words】 Hemoglobin A; Diabetes mellitus, type 1, fulminant