·糖尿病与妊娠·

　　【摘要】 目的 分析胰岛素泵连续皮下输注(CSII)治疗GDM的临床效果。 方法 选择GDM和糖尿病合并妊娠患者共103例，分为CSII组和胰岛素多次皮下注射(MSII)组,比较两组血糖控制情况及母婴并发症的发生情况。 结果 治疗5 d后，两组FPG、1 hPG、2 hPG、28、36周HbA1c、血糖达标天数、胰岛素用量比较,差异均有统计学意义(P<0.01)。两组母体低血糖、早产的发生率及胎儿低血糖的发生率比较，差异均有统计学意义(P<0.01或P<0.05)。 结论 胰岛素泵控制GDM和糖尿病合并妊娠的血糖更快、更平稳,并可减少低血糖的发生,其临床应用效果优于传统的胰岛素多次皮下注射方式。

　　【关键词】 妊娠期糖尿病;糖尿病合并妊娠;胰岛素泵;多次皮下注射

　　【Abstract】 Objective To analyze the clinical effects of continuous subcutaneous insulin infusion (CSII) on gestational diabetes mellitus. Methods 103 diabetic patients with gestational diabetes mellitus and diabetic pregnancy were divided into CSII group and multiple subcutaneous insulin injection (MSII) group .The sugar blood control and the occurrence rates of maternal and fetal complications were compared between the two groups. Results after 5 days,there were statistically significant in FPG, 1 hPG, 2 hPG,HbA1c of 28 and 36 weeks, , the time to target blood glucose ,insulin dosage,the incidence of preterm delivery and hypoglycemia between the two groups (P<0.01 or P<0.05). Conclusion CSII is superior to MSII therapy in sugar blood control and the occurrence rate of hypoglycemia, its clinical effect is better than that in traditional insulin subcutaneous injection.

　　【key words】 Gestational diabetes mellitus(GDM); Diabetes complicating pregnancy; Insulin pump; Multiple insulin injection mellitus; Blood sugar control; Complications. Neonatal outcomes