·糖尿病胰岛素治疗·

　　【摘要】 目的 探讨糖尿病治疗中应用胰岛素治疗时，一过性屈光不正的发生率及其临床特点。 方法 纳入糖尿病患者160例，男76例，女84例，年龄18～65岁，平均(56.26±8.13)岁。研究对象均为初次应用胰岛素的糖尿病患者,其中59例在治疗中出现一过性视物不清，后证实为屈光不正。对屈光不正的度数、出现时间、持续时间、恢复时间、血糖下降幅度、胰岛素用量进行分析。 结果 初次应用胰岛素的糖尿病患者,出现一过性视物不清发生率为36.9%(59/160)，出现视物不清患者屈光度均为远视，表现为波动性屈光不正，屈光变化的程度和性质与血糖变化程度、TG及年龄有关，与胰岛素用量与HbA1c无关。 结论 糖尿病患者应用胰岛素治疗时，随着血糖的下降会出现远视性屈光不正。

　　【关键词】 胰岛素;糖尿病;屈光不正

The study on insulin ametropia GUO Zheng-dong, HUANG Dong-hui, TANG Xian-ge, et al. Department of Endocrinology, the Affiliated Hospital of Taishan Medical College, Shandong 271000, China

　　【Abstract】 Objective To explore the incidence rate and its clinical characteristics of transient ametropia while use insulin treatment diabetes mellitus patients. Methods Of all the 160 cases of diabetes mellitus, with 76 male and 84 female, age range was 18 to 65 years. The average age is (56.26±8.13) years. All the patients were diagnosed of diabetes mellitus and recieved insulin for the first time. During the insulin treatment, transient blurred vision were found in 59 patients and proved to be ametropia. The degree, the time of onset, duration, recovery time, the decrease of blood glucose, the dosage of insulin were analyzed. Results The occurrence rate of transient blurred vision was 36.9%(59/160). The blurred vision were all hypermetropia and volatile ametropia. The degree and the character of ametropia were correlated with age, the rapidly decreased glucose and extent of blood glucose fluctuation, and were correlated with glycosylated hemoglobin and the dosage of insulin. Conclusion Hypermetropia will appear accompanying decrease of blood glucose level in patients with diabetes mellitus who underwent the insulin treatment for the first time.

　　【Key words】 Insulin; Diabetes mellitus; Ametropia