【提要】 本文对1例Gitelman综合征(GS)伴IR患者进行报道。患者女，27岁，以低血钾(2.62 mml/L)、低血镁(0.33 mmol/L)、代谢性碱中毒(HCO3— 27.7 mmol/L)、低尿钙(1.25 mmol/24 h)、肾素及醛固酮增高、血压正常为主要特点。血糖正常，存在IR、Ins高峰后移、胰岛素曲线下面积(AUCI)388.6，经补钾、补镁治疗效果好。故临床低血钾、低血镁患者，应注意排除GS。

　　【关键词】 Gitelman综合征;胰岛素抵抗

Gitelman syndrome with insulin resistance:one case report YANG Wang-rong, LUO Zuo-jie, MENG Bi-hui ，et al. Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021,China

Corresponding author：LUO Zuo-jie,E-mail：zluo888@yahoo.com.cn

　　【Summary】 One case of GS patient with insulin resistance was reported.The female patient aged 27 years was diagnosed as Gitelman syndrome by the typical biochemical pictures including renal wasting hypokalemia(2.62 mmol/L),hypomagnesemia(0.33 mmol/L),metabolic alkalosis(HCO3—27.7 mmol/L)，hypocalciuria(1.25 mmol/24 h),high reninemic and aldosteronism and normal blood pressure.The patients showed a normal range glucose and a delay of insulin secretion peak of 120 min after a glucose load. The insulin area under curve(AUCI)was 388.6.O ral potassium and magnesium supplementation were efficacious,so GS should be considered in the differential diagnosis for the patient with hypokalemia and hypomagnesemia.

　　【Key Words】 Gitelman syndrome;Insulin resistance