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 血清尿酸与我国2型糖尿病患者视网膜病变的相关性研究

来自:中国糖尿病杂志  编辑: 曾静波 庄晓明 穆君|点击数:|2014-12-16

  糖尿病视网膜病变

  【摘要】 目的 探讨血清尿酸(SUA)与我国T2DM患者DR的关系。 方法 采用四分位法将T2DM患者SUA水平分为4组,眼底镜诊断有无DR。采用Logistic多元回归分析SUA与DR发病率的关系。 结果 SUM>211 μmol/L后即为DR危险因素,随着SUA升高,影响程度增加,OR值分别为3.85(1.98~6.84)、5.12(2.25~8.10)、5.71(2.99~8.87)。 结论 SUA是DR的危险因素,降低SUA水平应为其治疗的重要环节。

  【关键词】 血清尿酸;糖尿病,2型;糖尿病视网膜病变

  【Abstract】 Objective To investigate an association between serum uric acid (SUA) and DR. Methods All subjects were examined and basic information was recorded for inclusion criteria. Four groups were produced based on uric acid quartile levels. Logistic regression were used to analyze OR between SUA and the prevalence of DR. Results In the adjusted logistic regression models, prevalence of DR was significantly correlated with increase of SUA>211 μmol/L, OR 3.85(1.98~6.84), 5.12(2.25~8.10), 5.71(2.99~8.87), respectively. Conclusion Elevated SUA was associated with DR in Chinese T2DM patients. Monitoring of SUA provides a predictive value for treating DR.

  【Key words】Serum uric acid (SUA);Diabetes mellitus,type 2;Diabetic retinopathy (DR)

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