文献综述

　　【摘要】规律的运动锻炼可改善T2DM、肥胖症和心血管疾病等代谢性疾病。Irisin是新发现的肌肉因子，无论在啮齿类动物还是人体内，运动后irisin浓度均上升。推测Irisin可能具有促进白色脂肪棕色化、增加能量消耗、改善IR、调节糖脂平衡的作用。

　　【关键词】Irisin;运动;肌肉因子;糖脂代谢

　　【Summary】Regular exercise training can improve metabolic diseases such as T2DM, obesity and cardiovascular disease. Irisin is a novel myokine was recently identified, its concentration was increased significantly after exercise training in both mice and humans. It has been suggested that irisin might have many physiological functions, such as inducing white fat browning, increasing total energy expenditure, reducing IR and obesity, modulating glucose, and affecting lipid metabolism.

　　【Key words】Irisin;Exercise;Myokine;Glucose and lipid metabolisim