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 Turner综合征合并1型糖尿病、桥本氏甲状腺炎甲状腺功能减退1例报告

来自:中国糖尿病杂志  编辑:崔秀芳 康晓清|点击数:|2013-08-26

  ·病例报告·


  【摘要】 患者染色体核型46xi(xq),FPG14.57 mmol/L,2 hPG25.97 mmol/L,促卵泡生成激素(FSH)66.431(4~13 mIU/m),促黄体生成激素(LH)23.151 (1~18mIU/m),雌二醇E2<5.00(39~189 pg/ml)、甲状腺过氧化物酶抗体(TPOAb)38%(<20%),促甲状腺激素(TSH)12.85(0.35~0.50 uIU/ml)。根据患者生长、发育迟缓,染色体检查异常,C-P水平低下,血压140/100 mmHg,查体全身皮肤损坏。诊断Turner综合征合并T1DM、桥本氏甲状腺炎甲状腺功能减退、寻常型银屑病、高血压病。

  【关键词】Turner综合症;糖尿病,1型;甲状腺功能减退;高血压病

Turner′s syndrome accompanied with type 1 diabetes and hypothyroidism due to Hashimoto thyroiditis: a case report CUI Xiu-fang, KANG Xiao-qing. Department of Endocrinology, Wulanchabu Central Hospital, Wulanchabu 012000, China

  【Summary】This is a patient with Karyotype 46xi(xq), FPG 14.57mmol/L, 2 hPG 25.97 mmol/L, follicle-stimulating hormone (FSH) 66.43l (4~13mIU/m), luteinizing hormone (LH) 23.15l (1~18 mIU/m), estradiol E2<5.00 (39~189 pg/ml), antithyroid peroxidase antibody (TPOAb) 38% (<20%), and thyroid stimulating hormone (TSH) 12.85 (0.35~0.50 uIU/ml). She was diagnosed Turner′s syndrome accompanied with T1DM, hypothyroidism due to Hashimoto thyroiditis, ordinary psoriasis, and hypertension based on the features of her growth retardation, abnormal chromosomal karyotypes, low C-P level, BP 140/100mmHg, and skin lesions.

  【Key words】Turner′s syndrome; Diabetes mellitus, type 1; Hypothyroidism; Hypertension

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