·HbA1c测定和应用·

　　【摘要】 目的 探讨昆明地区T2DM患者HbA1c与FPG、2 hPG和血红蛋白(Hb)的关系，了解HbA1c的影响因素。方法 选取昆明市居住5年以上的T2DM患者208例，对HbA1c与FPG、2 hPG和Hb进行分析，高血红蛋白和正常血红蛋白组FPG、2 hPG和HbA1c进行比较。结果HbA1c与FPG、2 hPG呈正相关，相关系数分别为0.87、0.89，HbA1c与FPG和2 hPG的回归方程为Y=1.124+0.334X1+0.284X2。不同Hb水平间FPG、2 hPG和HbA1c比较差异无统计学意义。结论 影响HbA1c的主要因素是FPG和2 hPG，Hb对FPG、2 hPG和HbA1c无明显影响。

　　【关键词】糖尿病，2型;糖化血红蛋白;相关因素

Analysis on the influencing factors of HbA1c in T2DM patients in Kunming JU Hai-bing, XU Xin-ming, SHU Zi-zheng, et al. Department of Endocrinology, Kunming General Hospital of Chengdou Command, Kunming 650032,China

　　【Abstract】 Objectives To explore the correlation of HbA1c with the levels of hemoglobin (Hb),FPG, and 2 hPG, and to evaluate the influencing factors of HbA1c. Methods A total of 208 T2DM patients living in Kunming city were investigated. The correlation of HbA1c with Hb, FPG, and 2 hPG was studied. A comparison of the levels of FPG, 2 hPG, and HbA1c between the high and normal Hb groups was carried out for study. Results The HbA1c level was positively correlated with the FPG (r=0.87) and 2 hPG (r=0.89) levels. The regression equation of HbA1c with FPG and 2 hPG was Y=1.124+0.334X1+0.284X2. In different Hb levels there were no significant differences in the correlation of HbA1c with FPG and 2 hPG. Conclusion The major influencing factors of HbA1c are FPG and 2 hPG. The Hb level is not affecting the levels of FPG, 2 hPG, and HbA1c significantly.

　　【Key words】Diabetes mellitus, type 2; Hemoglobin A1c (HbA1c); Correlated factors