·胰岛素抵抗及其相关疾病·

　　【摘要】 目的 了解多囊卵巢综合征(PCOS)患者糖脂代谢及IR的特点。 方法 选取PCOS患者161例(PCOS组)及年龄匹配的健康女性150名(NC组)，比较两组的血糖、血脂及IR情况。 结果  PCOS组糖、脂代谢异常、肥胖发生率均高于NC组(26%vs3.3%， 34.7%vs10.1%，60%vs22.7%)，且血糖、血脂、BMI更高，IR加重(P<0.05)。 结论 多囊卵巢综合征患者具有糖脂代谢异常及IR，要积极纠正代谢紊乱，预防心血管事件。

　　【关键词】 多囊卵巢综合征;胰岛素抵抗

Characteristics of abnormal glycolipid metabolism and insulin resistance in women with polycystic ovary syndrome ZHEN Yue-qiao, WANG Dong-mei. Department of Endocrinology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

　　【Abstract】Objective To investigate the characteristics of abnormal glycolipid metabolism and IR in women with polycystic ovary syndrome (PCOS). Methods The 161 PCOS women and 150 age-matched normal women were enrolled in this study. The glycolipid metabolism and insulin resistance of the two groups were compared for analysis. Results Compared with the control group, the percentage of abnormal glycolipid metabolism and obesity was higher in the PCOS group (26% vs 3.3%, 34.7% vs 10.1%, 60% vs 22.7% respectively). Women with PCOS were found to have higher glucose, higher triglyceride, higher total cholesterol, higher LDL cholesterol, lower HDL cholesterol, higher BMI, and higher IR levels than their non-PCOS counterparts (P<0.05). Conclusions There are dysglycemia, dyslipidemia and IR in the PCOS patients. More attention should be paid to correcting the abnormal glycolipid metabolism to prevent cardiovascular events.

　　【Key words】Polycystic ovary syndrome (PCOS); Insulin resistance (IR)