·糖尿病临床研究·

　　H型高血压与老年糖尿病性脑梗塞的关系研究

　　张月 李华 岳欣阁 陈素芳 白杨 董捷

　　【摘要】 目的 探讨H型高血压与老年糖尿病性脑梗死的关系及意义。 方法 选取老年患者194例，比较T2DM组、糖尿病性脑梗塞(DCI)组、脑梗塞(CI)组与NC组血清同型半胱氨酸(Hcy)及H型高血压发生率的差异。 结果 血清Hcy在DCI组高于CI组、T2DM组及NC组，比较差异有统计学意义(P<0.05)。DCI组H型高血压发生率高于CI组及T2DM组(78.43% vs 68.97% vs 42.83%)，比较差异有统计学意义(χ2=9.73，P<0.05)。Logistic回归分析示,H型高血压可能为DCI的危险因素(OR=3.86，P<0.05)。 结论 H型高血压在DCI的发生发展中起重要作用。

　　【关键词】 老年2型糖尿病;糖尿病性脑梗塞;H型高血压;同型半胱氨酸

H-type hypertension in elderly diabetic cerebral infarction Relationship ZHANG Yue，LI Hua，YUE Xin-ge，et al. Old age of Endocrinology，First Affiliated Hospital of Zhengzhou University，Zhengzhou450052,China

Corresponding Author：LI Hua，E-mail：lihuazzu@126.com

　　【Abstract】 Objective To study the relationship between type H hypertension and diabetic cerebral infarction. Methods A total of 89 senile T2DM and 106 diabetic cerebral infarction(DCI) patients and 87 cerebral infarction(CI) patients were recruited into our study.And 88 healthy elderly were included as NC.The biochemical parameters and anthropometric indices were determined using standard procedures. Results The serum Hcy were significantly higher in the DCI group when compared with the CI,T2DM and NC group(P<0.05﹚.Incidence rate of type H hypertension in the DCI group was higher than CI,T2DM group (78.43% vs 68.97% and 42.83%;χ2=9.73, P<0.05).Logistic regression analysis showed that type H hypertension are risk factors for DCI (OR value:3.86, P<0.05). Conclusion Type H hypertension may play an important role in DCI.

　　【Key words 】 Elderly T2DM patients;Diabetic cerebral infarction; H-type hypertension; Homocysteine