【摘 要】 目的 探讨T2DM患者血糖控制情况及不同抗糖尿病治疗方案对HbA1c达标的影响。 方法 横断面调查2008～2009年300例T2DM患者的HbA1c达标情况及其与抗糖尿病治疗方案的关系。 结果 ①T2DM患者HbA1c<6.5%和7.0%分别为38.3%和51.7%;②不同治疗方案组中，胰岛素联合口服药物组HbA1c最高(P<0.05);③口服药物组中，三种及以上药物组HbA1c最高(P<0.05)。 结论 低胰岛素使用率是T2DM患者血糖控制不良的因素之一，启动胰岛素治疗有望改善血糖控制状态。

　　【关键词】 糖尿病，2型;糖化血红蛋白;糖基化;达标;胰岛素

　　Relationship between the anti-diabetic regimens and blood glucose control in type 2 diabetic patients CHENG Xin, YE Shan-dong, CHEN Yan. Department of Endocrinology, Anhui Provincial Hospital，Hefei 230001, China

　　Corresponding author: YE Shan-dong, E-mail：ysd6464@ yahoo.com

　　【Abstract】 Objective To investigate the status of blood glucose control in type 2 diabetic patients and the influence of different treatments on their target level of HbA1c. Methods In this cross section investigation, the hemoglobin A1c (HbA1c) and personal anti-diabetic regimens of 300 type 2 diabetic patients in 2008～2009 were recorded and then the relationship between the target level of HbA1c and different treatments was analyzed. Results ①. Of the 300 patients, the HbA1c <6.5% & <7% was 38.3% & 51.7% respectively. ②. Of the groups with different treatments, the HbA1c was the highest in the group treated by insulin combined with oral anti-diabetic drugs (P<0.05). ③. Of the oral anti-diabetic drug groups, the HbA1c was the highest in the group treated by 3 and more drugs (P<0.05). Conclusion The conservative anti-diabetic regimens is an important factor for the poor blood glucose control in type 2 diabetic patients. Application of insulin early is helpful in improving the blood glucose control.

　　【Key words】Diabetes mellitus, type 2; Hemoglobin A1c (HbA1c); Glycosylate; Reaching the target; Insulin