【摘要】 T2DM和阻塞性睡眠呼吸暂停综合征(OSAS)均是具有潜在危险的现代常见病，并常常在肥胖病人中同时存在。本文报告1例肥胖T2DM伴OSAS的患者，经人胰高糖素样肽-1类似物利拉鲁肽联合二甲双胍治疗3个月，血糖控制平稳、体重下降。该治疗方案为解决此类患者的问题提供了新的选择。

　　【关键词】 利拉鲁肽;糖尿病，2型;阻塞性睡眠呼吸暂停综合征

　　Liraglutide combined with metformin in the treatment of obese T2DM patients accompanied with obstructive sleep apnea syndrome: A case report DONG Yue-hua, ZHU Mei, GAO Zhi-hong. Department of Endocrinology, General Hospital, Tianjin Medical University, Tianjin 300052, China

　　Corresponding author: ZHU Mei, E-mail: meichuqin@yahoo.com.cn

　　【Summary】 Both type 2 diabetes mellitus (T2DM) and obstructive sleep apnea syndrome (SAS) are common diseases having high potential hazards and clinically they are always co-existing, especially in obese patients. In this report, an obese patient with T2DM and OSAS was treated with human glucagon-like peptide-1 analogue liraglutide plus metformin for 3 months, and the effect was good in glycemic control and weight loss. Such a successful treatment may provide a new option for treating the similar patients.

　　【Key words】Liraglutide; Diabetes mellitus, type 2; Obstructive sleep apnea syndrome