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江苏省不同糖耐量人群代谢综合征的患病率研究

来自:中国糖尿病资讯网  编辑:lj|点击数:|2011-10-20

江苏省不同糖耐量人群代谢综合征的患病率研究

·糖尿病临床研究·

作者单位:210008南京大学医学院附属鼓楼医院内分泌科(项守奎、毕艳、胡云、童国玉、张宁、朱大龙);常州市第二人民医院内分泌科(成金罗);苏州市第四人民医院内分泌科(吕国萍);江苏大学附属医院内分泌科(陈军建);南通大学附属医院内分泌科(崔世维);淮安市第二人民医院内分泌科(俞伟男)(第一作者现在常州市第一人民医院工作)

通讯作者:朱大龙, E-mail: zhudldr@gmail.com

项守奎 毕艳 胡云 童国玉 张宁 成金罗 吕国萍 陈军建 崔世维 俞伟男 朱大龙

【摘要】 目的 比较江苏省不同糖耐量人群代谢综合征(MS)的患病率。 方法 采取整群随机抽样 方法 ,内容包括体检、75g葡萄糖耐量试验(OGTT)及检测血脂等,并根据OGTT 结果 分为正常糖耐量(NGT)组、糖调节受损(IGR)组和2型糖尿病(T2DM)组。 结果 (1) NGT组、IGR组和T2DM组的MS的患病率分别为16.3%、47.6%及64.6%。(2) T2DM组女性MS患病率显著高于男性(72.6% vs 53.1%),而NGT组及IGR组MS患病率男女之间无统计学差异(IGR组:53.9% vs 39.8%;NGT组:16.7% vs 15.7 %)。(3)从NGT→IGR→T2DM,MS患者中合并3种MS组分者的比例逐渐减少,而合并4种及5种MS组分者的比例逐渐增多。 结论 在T2DM前期IGR阶段,MS患病率已经显著升高;T2DM患者常合并多种代谢异常,是MS的高发人群。

doi:10.3969/j.issn.1006-6187.2011.06.009

Prevalence of metabolic syndrome in Jiangsu adults with different glucose tolerance

XIANG Shou-kui, BI Yan, HU Yun, et al. Department of Endocrinology, Affiliated DrumTower Hospital of Nanjing University Medical School, Nanjing 210008, China

Corresponding author: ZHU Da-long, E-mail: zhudldr@gmail.com

【Abstract】 Objective To study the prevalence of metabolic syndrome (MS) in Jiangsu adults with different glucose tolerance. Methods With randomized cluster sampling, physical examination, 75g oral glucose tolerance test and blood lipids measurement were performed in people from five cities of Jiangsu province. The study subjects were then divided into normal glucose tolerance group(NGT), impaired glucose regulation group(IGR) and type 2 diabetes mellitus group(T2DM) according to the Results of OGTT. Results (1) The MS prevalence in NGT group, IGT group and T2DM group were 16.3%、47.6% and 64.6% respectively. (2) The MS prevalence was higher in female than in male of T2DM group(72.6% vs 53.1%, P<0.05), while there was no significant difference in MS prevalence between male and female population in IGR versus NGT group(53.9% vs 39.8%) and (16.7% vs 15.7%). (3) From NGT to IGR to T2DM, constituent ratio of people with 3 MS components decreased gradually, while constituent ratio of people with 4 or 5 MS components increased gradually. Conclusion s The MS prevalence increases significantly in prediabetes. Type 2 diabetic patients are often associated with a variety of metabolic abnormalities, and have a high risk of MS.

【Key words】Impaired glucose tolerance; Diabetes mellitus, type 2; Metabolic syndrome; Prevalence rate

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