·糖尿病心血管病·

         马立萍、李全民

　　作者单位：100029首都医科大学北京安贞医院普内科糖尿病组(马立萍);解放军第二炮兵总医院内分泌科(李全民)

　　摘要】目的  分析急性冠状动脉综合征患者经皮冠状动脉介入治疗(PCI)术后患者住院期间的平均血糖水平与患者预后的相关性。方法  查阅2009年1月至12月在我院心内科以急性冠状动脉综合症合并糖尿病的患者入院并进行PCI治疗的患者1723例，且住院时间不少于3 d。住院期间每日监测血糖不少于4次的患者的病例资料，根据住院期间不同的平均血糖值(MBG)分组，观察MBG与不良心血管事件发生数、死亡数的相关性。结果  各组患者住院期间MBG为7.8~11.0 mmol/L的患者，主要不良心血管事件发生率及死亡率显著低于平均血糖<7.8 mmol/L和>11.0 mmol/L组(P<0.05)。结论  提示在糖尿病合并PCI术后住院期间患者的平均血糖水平控制在(7.8~11.1 mmol/L) 范围内时安全性好，死亡率低。

　　【关键词】PCI术后;血糖; 糖尿病;心血管事件; 死亡

　　doi:10.3969/j.issn.1006-6187.2011.12.005

　　The relationship of a prognosis with the average blood glucose after percutaneous coronary intervention (PCI) in acute coronary syndrome patients during hospitalizationMA Li-ping, LI Quan-min. Department of Endocrinology, Beijing Anzhen Hospital of the Capital University of Medical Sciences, Beijing 100029,China

　　【Abstract】   Objective   To analyze the relationship between a prognosis and the average blood glucose after percutaneous coronary intervention (PCI) in acute coronary syndrome patients during hospitalization.   Method   This retrospective study included 1723 post-PCI patients with acute coronary syndrome and diabetes during January to December 2009.The daily blood glucose monitoring was no less than 4 times during hospitalization. The relationship of the average blood glucose (MBG) with the incidence of death and adverse cardiovascular events was studied.    Results   The incidence rates of major adverse cardiovascular events and mortality were lower in group with MBG of 7.8-11.0 mmol/L than in groups with MBG<7.8 and >11.0 mmol/L (all P<0.05).   Conclusion   The average blood glucose level of diabetic patients after PCI should be controlled at the safety range between 7.8-11.1 mmol/L during hospitalization to decrease mortality.

　　【Key words】Post- PCI; Blood glucose; Diabetes; Cardiovascular events; Death