【摘要】 随着全球超重/肥胖患病率的上升和研究的累积，人们逐渐认识到超重/肥胖在心血管疾病及死亡中发挥的重要作用。本文从超重/肥胖的诊断及分级出发，通过回顾流行病学证据，初步探讨了其导致心血管疾病及死亡的可能机制，并围绕体重与心血管结局之间的关系展开论述。此外，对于体重的管理，除了生活方式及药物干预之外，尤其应关注降糖药物对糖尿病患者体重的不同影响。

【关键词】体重；心血管疾病；心血管死亡

The relationship between body weight and cardiovascular mortality

LÜ Ju-ming, Endocrinology Department, The General Hospital of People’s Liberation Army,Beijing 100853,China

【Abstract】 As the prevalence of overweight and obesity is increasing globally and more and more studies focused on it, it has been recognized that overweight and obesity play an important role in cardiovascular disease and death. This article reviewed the diagnosis and classification of overweight/obesity, and introduced the mechanism and relationship between body weight and cardiovascular mortality. We also recommend the management of obesity by lifestyle intervention and drugs treatment, including the effect of anti-diabetic drugs on body weight for diabetes patients.

【Key words】Body weight; Cardiovascular mortality; Cardiovascular diseases