【摘要】 目的 探讨T2DM患者胆囊排空功能改变及与胆囊动脉血流动力学的关系。 方法 超声测定胆囊体积、胆囊排空功能及胆囊动脉血流。 结果 T2DM组较NC组空腹胆囊体积(FV)及脂餐后胆囊体积(RV)增大，胆囊排空率(EF)减低(P<0.01);胆囊动脉阻力指数(RI)升高[(0.61±0.06) vs (0.70±0.08)](P<0.01)，舒张期最低流速(Vmin)降低[(8.72±1.43) vs (6.05±1.89) ](P<0.01)。相关分析结果显示，胆囊动脉RI与HbA1c、LDL-C呈正相关(r=0.827, 0.820,P<0.01)。 结论 T2DM患者胆囊排空功能减低与胆囊动脉血流动力学改变相关。

　　【关键词】 糖尿病，2型;胆囊排空;动脉;超声检查

　　Relationship of gallbladder emptying function and its hemodynamics in diabetic patients LU Li-jun，YAN Xiang，MA Su-mei.Department of Ultrasonography, The First Hospital of Lanzhou University, Lanzhou 730000, China

　　【Abstract】 Objective To explore the relationship of gallbladder emptying function and its hemodynamics in diabetic patients. Methods Gallbladder volume, emptying function and its arterial blood flow were measured by ultrasound. Results The gallbladder volumes of fasting(FV) and postprandial(RV) increased and the ejection fraction(EF) of gallbladder was decreased in DM group than in NC group (P<0.01). In DM group, The gallbladder artery's resistance index (RI) was higher than in NC group [(0.61±0.06) vs (0.70±0.08)](P<0.01). Minimum diastolic blood flow velocity (Vmin) was lower than in NC group [(8.72±1.43)vs (6.05±1.89)](P<0.01). RI was associated with HbA1c (r=0.827,P<0.01) and LDL-C(r=0.820,P<0.01). Conclusion Gallbladder emptying dysfunction in diabetic patients is associated with the hemodynamics of gallbladder.

　　【Key words】 Diabetes mellitus;Gallbladder emptying;Artery;Ultrasonography