【摘要】 目的 观察T2DM伴慢性牙周炎在降血糖治疗的基础上加用牙周炎治疗的临床效果。 方法 T2DM伴慢性牙周炎患者120例随机分为治疗组和对照组，对照组采用常规降糖治疗，治疗组在对照组的基础上加用牙周基础治疗。比较治疗前与治疗6周后各项指标。 结果 两组治疗前牙周袋探诊深度(PD)、附着丧失(AL)、菌斑指数(PLI)、牙龈出血指数(BI)、高敏C反应蛋白(hsC-RP)水平比较差异无统计学意义(P>0.05)。治疗组治疗后PD、AL、PLI、 BI、hsC-RP 较治疗前及对照组降低[PD：(2.51±0.68)，(2.42±0.31)vs(2.11±0.28)mm;AL：(3.58±0.83)，(3.49±0.58)vs(3.18±0.41)mm;PLI：(0.96±0.33)，(0.78±0.26)vs(0.41±0.21);BI：(2.65±1.21)，(1.14±0.30)vs(0.97±0.32);hsC-RP：(3.29±2.88)，(2.72±1.51)vs(1.02±0.63)mg/L](P<0.05)。 结论 T2DM伴慢性牙周炎在降糖治疗的基础上加用牙周炎治疗可减少炎性因子水平。

　　【关键词】 糖尿病，2型;慢性牙周炎;临床效果

　　Analysis of clinical effect of periodontic treatment in type 2 diabetic patients with chronic periodontitis SUN Lu-quan,YANG Wen-hua.Department of stomatology,Tianjin Beichen Hospital, Tianjin 300400,China

　　【Abstract】 Objective To explore the clinical effect of periodontic treatment in type 2 diabetic patients (T2DM) with chronic periodontitis on basis of hypoglycemic therapy. Methods From September 2011 to January 2014, 120 T2DM patients with chronic periodontitis were selected and divided into treatment group and control group with 60 cases in each group. Patients in control group were treated with conventional hypoglycemic therapy. Patients in treatment group were treated with initial periodontal therapy additionally on basis of conventional hypoglycemic therapy. Probing depth (PD), attachment loss (AL), plaque index(PLI), bleeding index(BI) and hypersensitive C reactive protein (hsC-RP) levels were compared before and after 6 weeks treatment. Results PD,AL,PLI, BI,and hsC-RPlevels had no significant difference between two groups before treatment (P>0.05).PD,AL,PLI,BI and hsC-RP levels after treatment in treatment group were all significantly decreased [PD：(2.11±0.28) vs (2.51±0.68) and (2.42±0.31) mm;AL：(3.18±0.41) vs (3.58±0.83) and (3.49±0.58) mm;PLI：(0.41±0.21) vs (0.96±0.33) and (0.78±0.26);BI：(2.65±1.21) vs (1.14±0.30) and (0.97±0.32); hsC-RP：(1.02±0.63) vs (3.29±2.88) and (2.72±1.51) mg/L] as compared with those before treatment in treatment group and those after treatment in control group (P<0.05). Conclusion Levels of inflammatory factors will decrease when periodontic treatment is added to the antidiabetic therapy in T2DM patients with chronic periodontitis.

　　【Key words】 Diabetes mellitus,type 2; Chronic periodontitis; Clinical effect