糖尿病神经病变

　　【摘要】 目的 探讨T2DM患者窦性心率震荡(HRT)变化及意义。 方法 选取T2DM患者67例和健康对照(NC)者73名，行24 h动态心电图检查，分析HRT震荡初始(TO)、震荡斜率(TS)、TO和TS异常的发生率。 结果 T2DM组TO、TS值与NC组比较差异有统计学意义[(﹣0.5754±2.5435) vs (﹣1.9219±2.7912)，P<0.05;(3.7412±3.2121) vs (8.9048±7.1440)，P<0.01]。 结论 HRT可作为预测T2DM患者自主神经病变的检测方法。

　　【关键词】　　【Abstract】 Objective To explore the variation of heart rate turbulence (HRT) and its clinical value in T2DM patients. Methods A total of 67 T2DM patients and 73 normal control (NC) subjects were enrolled in this study. All the subjects were assigned to 24h holter monitoring. Turbulence onset (TO) and turbulence slope (TS) were calculated from holter records and incidence of abnormal TO and TS were compared in two groups. Results The values of TO, TS in T2DM group were significantly different from NC group [(﹣0.5754±2.5435) vs (﹣1.9219±2.7912)，P<0.05;(3.7412±3.2121) vs (8.9048±7.1440)，P<0.01]. Conclusion HRT can be used to predict autonomic neuropathy in T2DM patients.

　　【Key words】 Diabetes mellitus，type 2;Heart rate turbulence (HRT);Autonomic neuropathy