【摘要】 目的 探讨在非内分泌科室进行高血糖筛查的最佳方法。 方法 选取心内科和骨科新入院患者，随机血糖≥7 mmol/L或FPG≥5.0 mmol/L的非糖尿病患者，均行75 gOGTT，并检测FPG、HbA1c、糖化血清蛋白(GA)，评估患者糖代谢情况。 结果 (1)心内科IGR、糖尿病和糖耐量正常(NGT)者分别185、178、163例，骨科116、130、107例。(2)75 gOGTT ROC曲线图显示，以FPG为诊断糖尿病切点，心内科为5.81 mmol/L，骨科为6.24 mmol/L;以HbA1c为诊断切点为，心内科6.15%,骨科5.75%;以GA为诊断切点，心内科为254.50 μmol/L，骨科250.89 μmol/L。(3)FPG和HbA1c联合诊断价值与75 gOGTT比较，有效性更高(AUC>0.8)。 结论 HbAlc与FPG联合检测能进一步提高非内分泌科住院患者的高血糖筛查效率。

　　【关键词】 住院患者，非内分泌科;空腹血糖;糖化血红蛋白;糖化血清蛋白;高血糖筛查

　　【Abstract】 Objective To expolre the better method for screen diabetes in patients of non-endocrinology departments. Methods The patients in department of cardiology and orthopedics whose random blood sugar≥7 mmol/L or fasting blood sugar≥5.0 mmol/L would detected with 75 gOGTT， FPG, HbAlc and glycated albumin(GA) Results (1)Based on 75 gOGTT, the patients were divided into impaired glucose regulation(IGR), diabetes mellitus and normal glucose tolerance (NGT)groups. There were 185、178、163 cases in IGR, diabetes mellitus and NGT groups in cardiology department and 116、130、107 cases in orthopedics department.(2)Based on the ROC curve，the optimal cut-point of FPG related to diabetes was 5.81 mmol/L in cardiology department and 6.24 mmol/L in orthopedics department. The cut-point of HbA1c was 6.15% in cardiology department and 5.75% in orthopedics department. The cut-point of GA was 254.50μmol/L in cardiology department and 250.89 μmol/L in orthopedics department. (3)The area under the curve(AUC)was 0.831 of FPG combined with HbAlc which was better than that of OGTT. Conclusion Combined detection of FPG and HbAlc is helpful to screen the undiagnosed diabetes patients.

　　【Key words】 Hospitalized patients, non-endocrinology ;Fasting plasma glucose;Hemoglobin A1c;Glycated albumin; Screening high glucose