【摘要】随着全球糖尿病患病率的不断攀升，糖尿病患者群呈现多样化的特点。除了成人T1DM和T2DM外，儿童和青少年糖尿病、妊娠期糖尿病(GDM)及老年糖尿病患者人数也不断增多。针对不同人群的特点和对血糖控制的特殊要求，多项国际指南均强调以患者为中心的治疗理念，设定个体化的血糖控制目标和治疗方案。速效胰岛素类似物门冬胰岛素，拥有广泛的适用人群，用于胰岛素强化治疗方案可有效控制餐后血糖，降低低血糖发生风险，且门冬胰岛素餐前或餐后即刻注射均可安全有效控糖，注射方式灵活方便，能更好地满足不同糖尿病患者的个体化血糖管理的需求，提高患者的生活质量和治疗依从性，从而实现更好的血糖控制。

　　【关键词】糖尿病;个体化管理;门冬胰岛素

　　【Abstract】With the prevalence of diabetes mellitus, the patient demography is changing greatly. In addition to adult type 1 and type 2 diabetes, the number of patients with diabetes in children and adolescents, pregnant womenand elder are increasing rapidly. On account of the difference andspecial requirements for diabetes management of different patients, a number of international guidelines emphasize apatient-centeredapproach and set special goalsand individual therapies for glycaemic control. Insulin aspartas a rapid-acting insulinanaloguecan be used in a broad range of patient types. When used in insulin intensification therapy, insulin aspartdemonstrates the efficacy and safety profile, offers flexible dosing, which prove to help reach the aged-special HbA1c goals and improve the quality of life.

　　[Key words] Diabetes mellitus;Individual management;Insulin aspart