【提要】接受Roux-en-Y胃空肠吻合术患者2例(术前T2DM及胃溃疡各1例)，术后均出现发作性低血糖反应，OGTT试验显示餐后高胰岛素、C-P分泌，胰腺影像检查未见明显异常，予饮食调整联合α-糖苷酶抑制剂治疗均有效。

　　【关键词】Roux-en-Y胃空肠吻合术;低血糖;糖尿病

　　Hyperinsulinemic hypoglycemia after Roux-en-Y anastomosis: A report on 2 cases GUO Yan, ZOU Da-jin. Department of Endocrinology, Shanghai Changhai Hospital, Shanghai 200433, China

　　Corresponding author: ZOU Da-jin, Email: zwjd22@medmail.com.cn

　　【Summary】Two patients (one man with T2DM and another man with gastric ulcer) had postprandial symptoms of neuroglycopenia owing to endogenous hyperinsulinemic hypoglycemia after Roux-en-Y anastomosis surgery. There was no radiologic evidence of insulinoma. OGTT test showed the augmentation of insulin and C-P secretion. Hypoglycemic symptoms diminished after dietary modification and α-glucosidase inhibitor such as voglibose.

　　【Key words】 Roux-en-Y anastomosis; Hypoglycemia; Diabetes