【摘要】 目的 筛选心脑血管高危患者，进一步确诊心脑血管病，了解MS各组分与冠脉病变严重程度的关系。 方法 在本院行冠脉造影的274例冠心病患者分为MS组和非MS组，进行统计分析。 结果 MS组多支病变率(≥2支)、Gensini 积分高于非MS组。随着代谢异常组分个数的增加，多支病变率、Gensini积分也随之增加。同时，按照冠脉病变支数、Gensini积分四分位分组，随着病变严重程度的增高，MS患病率也增加。Logsitic回归分析提示餐后血糖、BMI是冠脉病变严重程度的独立危险因素。结论 MS与冠脉病变严重程度关系密切。随着代谢异常组分个数的累积，冠脉病变严重程度增加。餐后血糖及体重对冠脉病变的影响尤为重要，应引起重视。

　　【关键词】代谢综合征;冠脉病变;冠脉造影

　　Relationship between metabolic syndrome contents and severity of coronary artery lesions in patients with coronary heart disease NI Ya-fang, FENG Bo, WANG Hua, et al. Department of Endocrinology, Shanghai East Hospital, Tongji University, Shanghai 200120, China

　　Corresponding author: FENG Bo, E-mail: fengbo@medmail.com

　　【Abstract】 Objective To screen metabolic syndrome in patients with coronary heart disease (CHD) in order to find out high-risk people of cardiovascular disease and study the relationship between metabolic syndrome contents and severity of coronary artery lesions. Methods Angiographies of coronary arteries were performed in 274 CHD cases. They were divided into metabolic syndrome (MS) group and non-metabolic syndrome (NMS) group according to CDS standard. Results The incidence of multi-branch (≥2) lesion was higher in the MS group. Gensini scores increased in the MS group compared with that in the NMS group. The incidence of multi-branch lesion and the Gensini score increased with the increase in metabolic syndrome contents. MS prevalence was increased with the increase in branch number and quartile of Gensini score. Logistic regression analysis revealed that the postprandial blood glucose and BMI were independent risk factors for CHD. Conclusion There is close relationship between metabolic syndrome and the severity of coronary heart disease. The severity of coronary artery lesions increase with the increase in metabolic syndrome contents. More attention should be paid to the postprandial blood glucose and BMI because they play a more important role in severity of coronary artery lesion in clinic.

　　【Key words】 Metabolic syndrome; Coronary artery lesions; Coronary angiography