张思敏 纪立农

　　作者单位：100044北京大学人民医院内分泌科

　　通讯作者：纪立农，E-mail: jiln@bjmu.edu.cn

　　【提要】面对日益严峻的糖尿病发病形势，医务人员应提供更加积极有效的治疗干预措施。除生活方式和药物干预外，减肥手术成为肥胖T2DM患者的选择之一。手术治疗糖尿病的机制和术后肠促胰素的分泌密切相关。本文就手术治疗糖尿病的发展历史、研究机制等方面进行文献综述。

　　【关键词】减肥手术;糖尿病，2型;肠促胰岛素

　　doi:10.3969/j.issn.1006-6187.2012.04.021

The research progress on bariatric surgery in the treatment of type 2 diabetes  ZHANG Si-min, JI Li-nong. Department of Endocrinology, Peking University People’s Hospital, Beijing 100044, China

　　Corresponding author：JI Li-nong, E-mail: jiln@bjmu.edu.cn

　　【Summary】Facing to the increasing global diabetes crisis, health care providers should provide potent therapeutic interventions as more as possible. In addition to behavioural and medical approaches, the bariatric surgery becomes a powerful option to relieve diabetes in obese type 2 diabetic patients. The mechanism of bariatric surgery in the treatment of diabetes is considered to be associated with incretin. This paper is a literature review on the history and mechanism of bariatric surgery.

　　【Key words】Bariatric surgery; Diabetes mellitus，type 2; Incretin