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实时动态血糖监测系统联合胰岛素泵治疗在胃转流手术围手术期的应用

来自:中国糖尿病资讯网  编辑:editor|点击数:|2012-11-26

  实时动态血糖监测系统联合胰岛素泵治疗在胃转流手术围手术期的应用

  关争梅 高艳红 张利岩 罗敏 梁昂 高相楠 高宏凯

  【摘要】 目的 研究实时动态血糖监测系统(DGMS® Real-Time)联合胰岛素泵(CSII)治疗在胃转流手术(GBP)围手术期的应用。 方法 44例符合GBP术条件的T2DM患者随机分为实验组和对照组,实验组20例采用DGMS® Real-Time联合CSII治疗,对照组24例采用指尖血糖监测联合胰岛素持续静脉滴注及皮下胰岛素注射治疗。连续观察整个围手术期血糖水平、全天胰岛素用量、低血糖发生率、高血糖发生率。 结果 1.实验组术前、术中及术后各时间点平均血糖均低于对照组,差异有统计学意义(P<0.05或P<0.01)。2.实验组整个围手术期平均血糖、24 h胰岛素用量均低于对照组,差异有统计学意义(P<0.05)。3.实验组低血糖发生率、高血糖发生率均低于对照组,差异有统计学意义(P<0.05)。 结论 胃转流手术围手术期,DGMS® Real-Time联合CSII治疗优于指尖血糖监测联合胰岛素持续静脉滴注及皮下胰岛素注射治疗。

  【关键词】 糖尿病,2型;胃转流手术;实时动态血糖监测系统;胰岛素泵

  Application of combination of the DGMS® Real-Time and CSII in perioperative period of gastric bypass operation

  GUAN Zheng-mei, GAO Yan-hong, ZHANG Li-yan, et al. Department of General Surgery, the Chinese People’s Armed Police General Hosital, Beijing 100039,China

  Corresponding author: GAO Yan-hong, E-mail:wjghk@163.com

  【Abstract】 Objective To study the real-time dynamic glucose monitoring system (DGMS ® Real-Time) and continuous subcutaneous insulin infusion (CSII) used in combination for gastric bypass (GBP) patients in peri-operative period. Methods Forty-four T2DM patients undergoing GBP surgery were randomized into experimental group and control group. The experimental group, 20 cases, was treated with DGMS® Real-Time combining with CSII, while the control group, 24 cases, was treated with the fingertip blood glucose monitoring plus insulin infusion and subcutaneous insulin injection. The two groups were observed on the level of blood glucose, all-day insulin dosage, and incidence of hypoglycemia and hyperglycemia in the whole peri-operative period. Results 1. At different time points of pre-, intra-, and post-operative period, the level of blood glucose in the experimental group was lower than that of the control group, and the difference was statistically significant (P<0.05 or P<0.01). 2. The level of average blood glucose and 24h insulin dosage throughout the whole peri-operative period in the experimental group were lower than those of the control group, and the differences were statistically significant (P<0.05). 3. The incidence of hypoglycemia and hyperglycemia in the experimental group was lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion The treatment of DGMS® Real-Time combined with CSII is better in effect than the traditional fingertip blood glucose monitoring plus insulin infusion and subcutaneous insulin injection.

  【Key words】 Diabetes mellitus, type 2; Gastric bypass operation; DGMS® Real-Time; Continuous subcutaneous insulin infusion (CSII)

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