糖尿病临床流行病学

　　乌鲁木齐市城市汉族居民代谢综合征与冠心病及糖尿病关系的差异性研究

　　王宁 张红玉 陈龙 王英斌 蒋升 谢自敬

　　【摘要】 目的 对比分析乌鲁木齐市汉族居民MS各组分对冠心病(CHD)、糖尿病(DM)的不同影响。 方法 共纳入40岁以上汉族居民1180例，计算MS患病率，并比较MS各组分与CHD、DM的关系。 结果 乌鲁木齐市汉族居民MS患病率为44.0%。部分MS组分有性别差异，男性超重、高血压患病率高于女性(53.5% vs 46.0%;18.3% vs 13.1%);女性WC超标发生率高于男性(88.5% vs 84.5%)，差异均有统计学意义。调整年龄、性别后，对冠心病有影响的MS组分包括血糖异常、高血压和超重;而对血糖异常有影响的MS组分包括高血压、超重、低HDL-C和WC超标。 结论 乌鲁木齐市汉族居民MS的患病率高，MS组分对冠心病、血糖异常的影响有差异性。

　　【关键词】 代谢综合征;肥胖;高血糖;冠心病

　　Variability of contribution of metabolic syndrome to coronary artery disease and diabetes mellitus in the Han residents of Urumqi WANG Ning, ZHANG Hong-yu, CHEN Long, et al. The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

　　Corresponding author: XIE Zi-jing ,E-mail: xiezijing@medmail.com.cn

　　【Abstract】 Objective To analyze the influence of metabolic syndrome (MS) on the coronary heart disease (CHD) and diabetes mellitus (DM) of the Han population in Urumqi. Methods The 1180 patients, aged over 40-years-old, were enrolled. The prevalence of MS was calculated and the influence of different MS components on CHD and DM analyzed. Results The MS prevalence of Han population in Urumqi was 44.0%. The prevalence of obesity and hypertension in male were more than in female (53.5% vs 46.0%; 18.3% vs 13.1%), the prevalence of enlarged waist circumference (WC) in female was more than in male (88.5% vs 84.5%), and the differences were statistically significant. After the age and gender regulation, the MS components influencing CHD were pathoglycemia, hypertension, and overweight, while those influencing pathoglycemia included hypertension, overweight, low HDL-C and enlarged WC. Conclusions The prevalence of MS in Han population of Urumqi is high, and there is a difference in MS components influencing CHD and pathoglycemia.

　　【Key words】 Metabolic syndrome; Obesity; Hyperglycemia; Coronary heart disease