【摘要】 目的 了解糖化血红蛋白水平，分析与人体指标的相关因素。 方法 用日本Tosoh HLC- 723 G7型全自动糖化血红蛋白分析仪对45岁以上企业职工进行了HbA1c检测，与FPG、TC、TG、h-CRP、WBC、NC#及脂肪肝人群进行分析。 结果 HbA1c 男性2783例为 5.52±0.79%，女性1603例为 5.49±0.63%,男女性别间比较无显著差异(P>0.05);HbA1c与FPG 结果的回归方程为：YHbA1c=0.541X+2.707 r=0.7679。DM检出277人，占受检人数6.32%，男女比例为：2.46:1。DM人群组TG、WBC、NC#、h-CRP与正常组比较具有显著差异(P<0.05)。脂肪肝患者的HbA1c、FPG、TG三项目结果显著高于正常人群(P<0.05)。 结论 DM检出率HbA1c项目高于血糖测定，HbA1c、FPG的结果随年龄的增长而增高，DM患病率男性高于女性。HbA1c与TG、h-CRP、WBC、NC#及脂肪肝患病有关。

　　【关键词】糖化血红蛋白;糖尿病;脂肪肝

　　A Survey of Glycohemoglobin Levels of 4,386 Staff and Workers Hu Shouyue. Zhang Yanming, Lin Jianpei Lianhua Hospital, Zhenhai District, Ningbo, Zhejiang 315207

　　【ABSTRACT】 Purpose: To understand the glycohemoglobin level, and analyze its relationship with human physiological index. Method: The HbA1c level was measured for enterprise employees with an age of 45 or above, using Japanese Tosoh HLC-723 G7 automatic glycohemoglobin analyzer, and the FPG, TC, TG, h-CRP, WBC, NC# levels were compared and analyzed against fatty liver population. Result: The HbA1c was 5.52±0.79% for 2,783 males, and 5.49±0.63% for 1603 females, indicating that there was no significant gender difference(P>0.05); The regression equation between HbA1c and FPG is: YHbA1c=0.541X+2.707 r=0.7679.DM was detected for 277 persons, accounting for 6.32% of the subjects, and with a male to female ratio of 2.46:1. There was a significant difference (P<0.05) in TG, WBC, NC#, and h-CRP between DM population and normal population. The HbA1c, FPG, and TG levels of fatty liver patients were significantly higher than normal population. Conclusion: HbA1c testing demonstrates a higher DM detection rate than blood glucose testing; HbA1c and FPG levels increase with age; and DM prevalence is higher for males than for females.HbA1c, TG, h-CRP, WBC, and NC# levels are related with fatty liver disease.

　　【Key Words】 Gycohemoglobin,;Diabetes;Fatty liver disease