·糖尿病临床研究·

　　黄菊芳 蒋培培 王鹂 彭妙官 许燕莉 黎福梅 廖志红

　　作者单位：510080广州，中山大学附属第一医院东山院区内科

　　通讯作者：廖志红，E-mail:liaozhh@mail.sysu.edu.cn

　　【摘要】 目的 在有或无疑似餐后低血糖症状的受试者中进行5小时口服葡萄糖耐量试验(5hOGTT)，探讨OGTT特征及其临床应用价值。 方法 共纳入27例有疑似餐后低血糖症状的受试者和41例无餐后低血糖症状的受试者，均行82.5g葡萄糖的5hOGTT。 结果 在无餐后低血糖症状的受试者中共筛查出低血糖6例。在有疑似餐后低血糖的受试者中共筛查出低血糖17例，低血糖再现率83%。诊断服糖后低血糖的人群中IGT伴发率达30%。 结论 与无餐后低血糖症状人群相比，有疑似餐后低血糖人群中服糖后低血糖的发生率高达63%，服糖后低血糖病例的 IGT伴发率达29%。对有疑似餐后低血糖病例进行4hOGTT低血糖筛查敏感性达100%。

　　【关键词】口服葡萄糖耐量试验;餐后低血糖

　　doi:10.3969/j.issn.1006-6187.2011.11.014

　　The application of 5 hours oral glucose tolerance test in diagnosising postprandial hypoglycemia

　　HUANG Ju-fang，JIANG Pei-pei，WANG Li，et al. Department of Internal Medicine ，Dongshan Division ，First Affiliated Hospital of Sun Yat-sen University，Guangzhou 510080，China

　　Corresponding auther:Liao Zhi-hong,E-mail:liaozhh@mail.sysu.edu.cn

　　【Abstract】 Objective To discuss the characteristics and clinical value of OGTT，5-h OGTT was carried out in subjects with or without suspected postprandial hypoglycemia symptoms. Methods 27 subjects with suspected postprandial hypoglycemia symptoms and 41 subjects without postprandial hypoglycemia symptoms accepted 82.5g 5-h OGTT. Results In group without postprandial hypoglycemia symptoms, 6 cases hypoglycemia were detected. In group with suspected postprandial hypoglycemia symptoms, 17 cases hypoglycemia were detected. The reappearance rate of hypoglycemia was 83%. In all hypoglycemia cases, the incidence of IGT reached 30%. Conclusion As compared to the group without postprandial hypoglycemia symptoms，the incidence of hypoglycemia in the group with suspected post-prandial hypoglycemia symptoms is higher，reaching 63%.At the same time，the incidence of IGT reaches 29% . In patients with suspected postprandial hypoglycemia symptoms，the sensitivity of detecting hypoglycemia reaches 100% by 4-h OGTT.

　　【Key words】 OGTT;Hypoglycemia