【摘要】  目的  了解糖尿病导致听力损害的特征，探讨其发病的相关危险因素。  方法  选择T2DM患者（T2DM组）88例及健康体检者（Con组）56名，测定纯音测听阈值，比较两组听力的差异。  结果  T2DM组和Con组听力损害的发生率分别为68.2%和28.6%，比较差异有统计学意义(P＜0.01)。T2DM组男性听力损害的发生率高于女性(61.7% vs 38.3%，P＜0.05），而Con组不同性别间比较，差异无统计学意义。T2DM组在所测试各个频率听力均有下降，高频听力下降更明显(P＜0.001）。T2DM组高频听力损害的发生率为45.4%（40/88），同时合并中低频听力损害发生率为17%(15/88)，仅存在中低频听力损害发生率为1.1%（1/88）。  结论  T2DM患者听力损害的比例较高,以高频听力损害为主,男性多见。

【关键词】  糖尿病，2型；听力损害；纯音测听

The features and risk factors of hearing impairment in type 2 diabetic patients   

【Abstract】  Objective  To assess the auditory function of patients with type 2 diabetes (T2DM), and to discuss the risk factors of hearing impairments.  Methods  Pure tone audiometry were measured in 88 pa-tients with T2DM (T2DM group) and 56 age-matched non-diabetic controls（Con group）.  Results  Compared with the control group, the incidence of hearing impairment in T2DM group increased(68.2% vs 28.6%，P＜0.01). In T2DM group, the proportion of hearing impairment in men was higher than in women(61.7% vs 38.3%，P＜0.05）; 45.4%（40/88） patients presented with high-frequency hearing impairment; 17% (15/88) combined with low/mid-frequency impairment; 1.1% （1/88）presented with only low/mid-frequency hearing impairment.  Conclusions  The incidence of hearing impairment is significantly increased in type 2 diabetic patients, with hearing loss mainly at high-frequencies, and more common in men.

【Key words】 Diabetes mellitus, type 2；Hearing impairment；Pure tone audiometry