来自:中国糖尿病杂志 编辑:程欣 何启胜 汪丹丹等|点击数:|2016-03-03
【摘要】 目的 分析T2DM患者的睡眠质量对血糖控制达标的影响及相关因素。 方法 T2DM患者205例,采用匹兹堡睡眠质量指数(PSQI)量表调查其睡眠质量。HbA1c<7%为血糖控制达标。以PSQI>5分为睡眠障碍,将患者分为睡眠良好组55例和睡眠障碍组150例。 结果 (1)T2DM患者伴发睡眠障碍的比例达73.2%(150/205);(2)与睡眠良好组比较,睡眠障碍组血浆皮质醇、HbA1c增高(t=-2.85、-3.87,P均<0.05), 血糖达标率降低(X2=6.959,P<0.05)。多元Logistic回归分析显示,HbA1c与睡眠障碍评分呈正相关(OR=3.74,P<0.05)。 结论 睡眠障碍在T2DM患者中发生率高,可能是影响HbA1c达标的因素之一。
【关键词】 糖尿病,2型;睡眠质量;血浆皮质醇;糖化血红蛋白
Clinical study on the relationship between sleep quality and glycemic control in patients with
type 2 diabetes
【Abstract】 Objective to investigate the effect of sleep quality on glycemic control in subjects with type 2 diabetic mellitus (T2DM). Methods A total of 205 inpatients with T2DM were enrolled in this study. Each patient completed Pittsburg Sleep Quality Index(PSQI) questionnaire. The glycemic control target was HbA1c<7%. Patients were divided into two groups : non-sleep disorder group(n=55), and sleep disorder group (n=150) defined as PSQI score >5 points. Results The incidence of sleep disorder was 73.2%(150/205) among all the subjects. Plasma cortisol and HbA1c in sleep disorder group were siginficantly higher (t=-2.85、-3.87,all P<0.05), whereas the rate of reaching glycemic control target was siginficantly lower(X2=6.959,P<0.05)than those of non-sleep disorder group. Multiple logistic regression analysis showed that glycemic control target was positively correlated with PSQI scores(OR=3.74,P<0.05). Conclusion The high inci-dence of sleep disorder in patients with T2DM may be one of the risk factors affecting glycemic control.
【Key words】 Diabetes mellitus,type 2;Sleep quality;Cortisol;Hemoglobin A1c
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