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2型糖尿病患者睡眠质量与血糖达标的相关性研究

来自:中国糖尿病杂志  编辑:程欣 何启胜 汪丹丹等|点击数:|2016-03-03

      

      摘要】   目的    分析T2DM患者的睡眠质量对血糖控制达标的影响及相关因素。 方法    T2DM患者205例,采用匹兹堡睡眠质量指数(PSQI)量表调查其睡眠质量。HbA1c<7%为血糖控制达标。以PSQI>5分为睡眠障碍,将患者分为睡眠良好组55例和睡眠障碍组150例。   结果 (1)T2DM患者伴发睡眠障碍的比例达73.2%(150/205);(2)与睡眠良好组比较,睡眠障碍组血浆皮质醇、HbA1c增高(t=-2.85、-3.87,P均<0.05), 血糖达标率降低(X2=6.959,P<0.05)。多元Logistic回归分析显示,HbA1c与睡眠障碍评分呈正相关(OR=3.74,P<0.05)。  结论     睡眠障碍在T2DM患者中发生率高,可能是影响HbA1c达标的因素之一。

        关键词】   糖尿病,2型;睡眠质量;血浆皮质醇;糖化血红蛋白

      Clinical study on the relationship between sleep quality and glycemic control in patients with 

type 2 diabetes 

       Abstract Objective    to investigate the effect of sleep quality on glycemic control in subjects with type 2 diabetic mellitus (T2DM).  Methods  A  total of 205 inpatients with T2DM were enrolled in this study. Each patient completed Pittsburg Sleep Quality Index(PSQI) questionnaire. The glycemic control target was HbA1c<7%. Patients were divided into two groups : non-sleep disorder group(n=55), and sleep disorder group (n=150) defined as PSQI score 5 points.   Results  The incidence of sleep disorder was 73.2%150/205 among all the subjects. Plasma cortisol and HbA1c in sleep disorder group were siginficantly higher (t=-2.85-3.87all P<0.05, whereas the rate of reaching glycemic control target was siginficantly lowerX2=6.959P<0.05than those of non-sleep disorder group. Multiple logistic regression analysis showed that glycemic control target was positively correlated with PSQI scoresOR=3.74P<0.05.  Conclusion   The high inci-dence of sleep disorder in patients with T2DM may be one of the risk factors affecting glycemic control.

    【Key words Diabetes mellitustype 2Sleep qualityCortisolHemoglobin A1c

 

上一篇:2型糖尿病合并血流感染的病原菌分布及耐药性分析 下一篇:2型糖尿病患者中性粒细胞/淋巴细胞与血糖水平的相关性研究

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