·点评·

方福德

作者单位：100005中国医学科学院北京协和医学院

【提要】 本文就不同人群PPARγ Pro12Ala多态性与2型糖尿病发病风险和易感性的相关性的Meta分析结果进行了评述，并就我国疾病遗传分析研究工作中所存在的相关问题作了点评，提出了相关的建议。

【关键词】 过氧化物酶体增殖物激活受体;糖尿病

doi:10.3969/j.issn.1006-6187.2011.07.001

PPARγ Pro12Ala: Old topic of conversation and new question

FANG Fu-de. Chinese Academy of Medical Sciences，Peking Union Medical College,Beijing 100005,China

【Summary】 Comments concerning meta analysis for relationship between PPARγ Pro12Ala polymorphism and type 2 diabetes susceptibility in different cohorts in this mini review were given. The comments pointed out existent problems and presented suggestions for genetic analysis of diseases in Chinese populations.

【Key words】 Peroxisome proliferation-activated receptor; Diabetes mellitus