·糖尿病临床流行病学·

　　【摘要】 目的 分析新疆维吾尔族(维族)IFG人群血脂代谢状况及LDL-C升高的危险因素。 方法 对新疆地区2053例30～80岁维族居民行横断面调查，筛查IFG人群，分析血脂代谢状况及LDL-C相关危险因素。 结果 该IFG人群中，血脂代谢异常的总患病率为99.8%(613/614)。高TG血症患病率为85.5%(525/614)，男女比较，差异无统计学意义(P>0.05);高TC血症、高LDL-C血症患病率为72.5%(445/614)和40.7%(250/614)，男性高于女性(75.0% vs 70.1%，52.4% vs 29.9%，P<0.05);低HDL-C血症患病率为29.8%(183/614)，男性低于女性(28.0% vs 31.4%，P<0.05)。Logistic回归分析显示，LDL-C升高的危险因素为年龄、TC、2 hPG。 结论 维族IFG人群血脂代谢异常的总患病为99.8%，其中LDL-C升高的患病率为40.7%，其危险因素为年龄、TC和2 hPG。

　　【关键词】 空腹血糖受损;高低密度脂蛋白血症;危险因素

　　【Abstract】 Objective To analysis the lipid metabolism abnormality and the risk factors of high LDL-C in patients with impaired fasting glucose(IFG) in Xinjiang Uygur. Methods A cross-sectional survey was conducted in 2053 cases of Uighur residents aged 30 to 80 years in Xinjiang. The lipid metabolism and the risk factors of high LDL-C were analyzed. Results In crowd with IFG, the overall prevalence of dyslipidemia was 99.8%(613/614). The prevalence of hypertriglyceridemia was 85.5%(525/614);the prevalence of hypercholesterolemia and high low-density lipoprotein was 72.5%(445/614) and 40.7%(250/614) respectively. The prevalence of hypercholesterolemia and high low-density lipoprotein was higher in male than in female (75.0% vs 70.1%, 52.4% vs 29.9%, P<0.05). The prevalence (male plus female) of low high-density lipoprotein was 29.8%(183/614) with lower prevalence in male than in female (28.0% vs 31.4%, P<0.05). Logistic regression analysis showed that independent risk factors for high low-density lipoprotein cholesterol were age, TC, 2 hPG. Conclusion The prevalence rate of all kinds of dyslipidemia is 99.8% of subjects with IFG in Xinjiang Uygur, and the prevalence of high low-density lipoprotein cholesterol was 40.7% of subjects with IFG . The independent risk factors for high low-density lipoprotein cholesterol were age, TC, 2 hPG.