糖尿病临床流行病学·

　　【摘要】 目的 了解近4年我国T2DM患者血糖控制状况及治疗情况变化。 方法 由中华医学会糖尿病学分会“糖化血红蛋白监测网”项目组于2009~2012年连续4年在全国范围内选择各省/市具有代表性的重点医院门诊就诊的T2DM患者参加本横断面研究，按照《数据采集标准操作流程(SOP)》询问患者。收集了解患者人口学信息、治疗方案、血糖控制情况，并填写至《监测网登记表》。以HbAlc<7.0%为达标。所有数据采用描述性统计分析。 结果 2009~2012年参加调研的T2DM患者分别为143123、172199、238656和223114例;至少有1种伴随疾病比例分别为63.8%、54.7%、52.1%和48.6%;平均HbAlc水平分别为7.97%、7.89%、7.85和7.74%;HbAlc达标率分别为35.28%、32.33%、31.77%和30.15。最常见的合并伴随疾病为高血压和血脂异常。 结论 我国T2DM患者HbAlc总体达标率低;约50%的T2DM患者合并至少1种伴随疾病。因此，多重危险因素的综合干预策略尤为重要。

　　【关键词】糖尿病，2型;糖化血红蛋白;口服降糖药;胰岛素;血糖控制

　　【Abstract】Objective To assess the status of glycemic control and treatment of T2DM in China in the last four years. Methods This was a cross-sectional study carried out all over China by Chinese Diabetes Society. Type 2 diabetic outpatients with antidiabetic drugs were included. Data on general characteristics, treatment regimen, complications and blood glucose levels were collected using a questionnaire interview.A glycated HbA1c of less than 7.0% was set as treatment target. Data were analyzed using descriptive statistics. Results From 2009 to 2012, 143123, 172199, 238656 and 223114 T2DM patients were enrolled, of 63.8%, 54.7%, 52.1% and 48.6% with at least one concomitant disease in each year respectively. The average HbAlC levels were 7.97%, 7.89%, 7.85 and 7.74%, in addition, 35.28%, 32.33%, 31.77% and 30.15% of the patients reached the target of HbA1c(<7%) respectively in each year. The most common concomitant diseases were hypertension and dyslipidemia. Conclusion (1) The overall rate of achieving HbA1c control target remained low among Chinese T2DM patients in the last four years. (2) About 50% of T2DM patients had at least one concomitant disease. So multifactorial risk reduction strategies beyond glycemic control is very important .

　　【Key words】Diabetes mellitus，type 2;Glycated hemoglobin HbAlc;Oral antidiabetic drugs;Insulin;Glycemic control