双月刊1993年10月创刊第14卷第2期2006年4月18日出版
目次
述评
加强肥胖研究，迎接新的挑战纪立农81

胰岛素抵抗及其相关疾病
LADA和2型糖尿病一级亲属胰岛
β细胞功能的变化邓志明周智广杨琳等84
非糖尿病人群肥胖相关指数与胰岛素
抵抗的关联年晓萍付方明董砚虎等88
肥胖患者脂肪组织抵抗素基因mRNA
表达的研究周剑时照明王佑民等90
游离脂肪酸对大鼠胰岛β细胞胰岛素分泌
及磺脲受体1基因表达的影响邓秀玲袁莉陈璐璐等92
细胞内脂肪堆积和β细胞增殖的
关系萧建中杨文英Kjeld Hermansen94

临床论著
MTP基因多态性与2型糖尿病血管并发症
的关系陈莉明孙蓓98
胃动素受体基因SNP位点的筛选及其与
糖尿病胃轻瘫的关系王志刚郑起贾伟平等101
PGC-1基因Gly482Ser多态性与
2型糖尿病的相关性研究单莉王辰纪立农等103
踝肱指数诊断糖尿病下肢动脉病变的
临床意义王爱红许樟荣王玉珍等105
糖尿病合并冠心病患者可溶性血管细胞
黏附分子1的变化石绮屏冯烈任强108
1型糖尿病患者胰岛素治疗前后内皮依赖性
血管舒张功能的变化向光大曹红燕曾尟枚等109
血清非酶糖基化终产物与糖尿病视网膜
病变的相关关系胡凯栾洁孙子林等112
老年2型糖尿病患者糖尿病肾病危险因素
分析孙丽荣王佳秋于德民等114
采用两种不同胰岛素制剂用胰岛素泵
长期治疗的差异马学毅荆丹清孙燕等116
新的空腹血糖受损切点对上海市浦东社区人群糖调节受损分布的影响李栩冯波倪亚芳等119
格列美脲治疗2型糖尿病的疗效观察杨华章陈亮裴剑浩等121

糖尿病教育
个体化饮食教育对糖尿病患者的干预效应范丽凤栾秀香郑亚光等123

基础论著
体外诱导大鼠骨髓间质干细胞分化为胰岛样细胞的研究孙吉平贾延劼宋建辉等126
糖尿病早期视网膜靶组织顶盖前区神经退行性病变的观察卢艳盛树力129
2型糖尿病大鼠心肌组织MMP-2、MMP-9、TIMP-1的表达与
胶原代谢的关系王绵张力辉邓永贵等133
高糖环境中真皮成纤维细胞生物学行为的变化王敏骏陆树良盛昭园等137
持续激活的Akt减少了 3T3-L1脂肪细胞脂联素蛋白的表达高萍李强孙予倩等142
咖啡因改善糖尿病大鼠膀胱功能的观察易超然卫中庆邓湘蕾等144
马来酸罗格列酮对大鼠血浆tPA和PAI-1活性的影响李红辉覃国珍丁殊节等146
应用SYBR Green I荧光定量RT-PCR测定糖尿病大鼠肾皮质
TGF-β1表达水平陈英剑涂晓文胡成进148

临床病例分析
糖尿病伴双下肢麻木无力邓正照肖文华洪天配等150

临床问答
5-羟色胺与糖尿病心血管并发症的关系林少达林楚佳152

基础研究与临床
内脏素又一新的脂肪因子徐伟斌俞璐罗敏153

综述
血管紧张素转化酶相关羧肽酶和糖尿病肾病范瑛汪年松155

讲座
空腹血糖受损与糖耐量减低的区别刘慧琳童南伟158

消息
本刊2005年度“胰岛素抵抗及其相关疾病”专栏优秀论文获奖作者名单83
参加本刊2005年度“胰岛素抵抗及其相关疾病”专栏优秀论文评选的获奖读者名单91
济南军区内分泌专业委员会等举办2006年代谢综合征新概念学术会议的通知113
国际糖尿病联盟-亚太区《2型糖尿病实用目标与治疗》第四版中文版出版115
2006年第二届北京国际糖尿病足及其相关疾病论坛第一轮通知118
北大维信举办“10年血脂康”百篇优秀论文评选活动通知122
中国中医药信息研究会关于选拔
“临床治疗配套行为干预处方体系构建研究课题组”课题学者的启事141
全国中西医结合内分泌代谢疾病学术会议征文通知160

国际著名儿童糖尿病学者贵田嘉一教授病逝149
更正87

CONTENTS IN BRIEF
Original Articles
Islet beta cell function in first-degree relatives of probands
with LADA and with type 2 diabetes84
DENG Zhi-ming, ZHOU Zhi-guang, YANG Lin, et al
Association of obesity indexes of waist circumference, body mass
index and WHR with insulin resistance in non-diabetic subjects88
NIAN Xiao-ping,  FU Fang-ming, DONG Yan-hu, et al
Study of resistin mRNA expression in adipose tissue of
Chinese obese individuals90
ZHOU Jian, SHI Zhao-ming, WANG You-min, et al
Effects of free fatty acids on insulin secretion and expression of
sulfonylurea receptor 1 (SUR1) gene in rat pancreatic β cells92
DENG Xiu-ling，YUAN Li，CHEN Lu-lu， et al
Accumulation of lipid and the proliferation of pancreatic islet beta cells94
XIAO Jian-zhong, YANG Wen-ying,  Kjeld Hermansen
Effect of microsomal triglyceride transfer protein（MTP） gene
polymorphism on angiopathy in type 2 diabetes98
CHEN Li-ming, SUN Bei
Primary screening of cSNP sites of human motilin receptor gene101
WANG Zhi-gang, ZHENG Qi, JIA Wei-ping, et al
Association  of  PGC-1  gene  Gly482Ser  polymorphism  with 
type 2  diabetes  mellitus103
SHAN Li, WANG Chen, JI Li-nong, et al
Ankle-brachial index in the diagnosis of peripheral artery disease
and its relationship with cardiovascular risk factors in the
patients with type 2 diabetes105
WANG Ai-hong,XU Zhang-rong,WANG Yu-zhen, et al
The inflammation response of sVCAM-1 in patients with coronary
artery disease and diabetes mellitus108
SHI Qi-ping, FENG Lie, Ren Qiang
The changes in endothelium-dependent arterial dilation before and after insulin treatment in type 1 diabetes109
XIANG Guang-da, CAO Hong-yang, ZENG Xian-mei, et al
The correlation between the advanced glycation end products (AGEs-P) and diabetic retinopathy112
HU Kai，LUAN Jie，SUN Zi-lin，et al
Study on the risk factors of diabetic nephropathy in older patients with type 2 diabetes114
SUN Li-rong, WANG Jia-qiu, YU De-min, et al
The differences between novolin R and novolog (aspart) during long period pump therapy116
MA Xue-yi， JING Dan-qing, SUN Yan， et al
Influence of the new cut point of impaired fasting glucose  on the distribution of IGR in Shanghai urban population119
LI Xu, FENG Bo, NI Ya-fang, et al
Efficacy of glimepiride in type 2 diabetes121
YANG  Hua-zhang, CHEN  Liang, PEI  Jian-hao, et al
Effect of individual diet education on management of diabetic patients123
FAN Li-feng, LUAN Xiu-xiang, ZHENG Ya-guang, et al
Rat bone marrow mesenchymal stem cells are induced to differentiate into islet-liking cells in vitro126
SUN Ji-ping, JIA Yan-jie, SONG Jian-hui,et al
The neurodegeneration of pretectal area in the early stage of diabetes129
LU Yan, SHENG Shu-li
The expression of MMP-2, MMP-9， TIMP-1 and the collagen metabolism in myocardial tissue of type 2 diabetic rats133
WANG Mian, ZHANG Li-hui, DENG Yong-gui, et al
Effects of high concentrations of glucose on the biological behavior of dermal fibroblast in diabetic rats137
WANG Min-jun,LU Shu-liang, SHENG Zhao-yuan,et al
Continuously activated Akt inhibits adiponectin secretion in 3T3-L1 adipocytes142
GAO Ping, LI Qiang, SUN Yu-qian, et al
Effects of caffeine on bladder dysfunction in diabetic rats144
YI Chao-ran, WEI Zhong-qing，DENG Xiang-lei，et al
Effect of rosiglitazone on plasma activity of tPA and PAI-1 in rats146
LI Hong-hui, QIN Guo-zhen, DING Shu-jie, et al
Measurement of transforming growth factor beta 1 mRNA expression in renal cortex of diabetic rats using
real-time reverse transcriptase-polymerase chain reaction  with SYBR Green I148
CHEN Ying-jian, TU Xiao-wen, HU Cheng-jin